Objective: To investigate the expression of nuclear factor kappa B ( NF-kB) and heparin-binding epidermal growth factor ( HB-EGF) in oviduct ampullar mucosa of normal, inflammatory and tubal ectopic pregnancy. 目的:探讨核因子kB(NF-kB)、肝素结合性表皮生长因子(HB-EGF)在人体正常、炎症、妊娠输卵管壶腹部黏膜表达及作用。
Results: NF-kB and HB-EGF were detected in all state of oviduct ampullar mucosa. The expression level of NF-kB was significantly higher in oviduct ampullar mucosa of inflammatory and tubal ectopic pregnancy than that in the normal group ( P < 0.01). 结果:人体正常、炎症、妊娠输卵管壶腹部黏膜上皮细胞均有NF-kB和HB-EGF表达,炎症组和妊娠组NF-kB的表达与正常组比较均显著增强,差异有极显著性(P<0·01);